Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes.

نویسندگان

  • Gavin Collie
  • Anthony P Reszka
  • Shozeb M Haider
  • Valérie Gabelica
  • Gary N Parkinson
  • Stephen Neidle
چکیده

Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.

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عنوان ژورنال:
  • Chemical communications

دوره 48  شماره 

صفحات  -

تاریخ انتشار 2009